Sterically confined rearrangements of SARS-CoV-2 Spike protein control cell invasion

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly contagious, and transmission involves a series of processes that may be targeted by vaccines and therapeutics. During transmission, host cell invasion is controlled by a large-scale (200–300 Å) conformational change of the Spike...

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Bibliographic Details
Main Authors: Esteban Dodero-Rojas, Jose N Onuchic, Paul Charles Whitford
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-08-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/70362