Immune Thrombocytopenia: Recent Advances in Pathogenesis and Treatments

Immune thrombocytopenia (ITP) is a rare autoimmune disease due to both a peripheral destruction of platelets and an inappropriate bone marrow production. Although the primary triggering factors of ITP remain unknown, a loss of immune tolerance—mostly represented by a regulatory T-cell defect—allows...

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Bibliographic Details
Main Authors: Sylvain Audia, Matthieu Mahévas, Martin Nivet, Sethi Ouandji, Marion Ciudad, Bernard Bonnotte
Format: Article
Language:English
Published: Wolters Kluwer 2021-06-01
Series:HemaSphere
Online Access:http://journals.lww.com/10.1097/HS9.0000000000000574