Purpurogallin, a Natural Phenol, Attenuates High-Mobility Group Box 1 in Subarachnoid Hemorrhage Induced Vasospasm in a Rat Model

High-mobility group box 1 (HMGB1) was shown to be an important extracellular mediator involved in vascular inflammation of animals following subarachnoid hemorrhage (SAH). This study is of interest to examine the efficacy of purpurogallin, a natural phenol, on the alternation of cytokines and HMGB1...

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Bibliographic Details
Main Authors: Chih-Zen Chang, Chih-Lung Lin, Shu-Chuan Wu, Aij-Lie Kwan
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:International Journal of Vascular Medicine
Online Access:http://dx.doi.org/10.1155/2014/254270