Investigation of the Syncytial Nature of Detrusor Smooth Muscle as a Determinant of Action Potential Shape

Unlike most excitable cells, certain syncytial smooth muscle cells are known to exhibit spontaneous action potentials of varying shapes and sizes. These differences in shape are observed even in electrophysiological recordings obtained from a single cell. The origin and physiological relevance of th...

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Bibliographic Details
Main Authors: Shailesh Appukuttan, Mithun Padmakumar, John S. Young, Keith L. Brain, Rohit Manchanda
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01300/full