Group 2 Innate Lymphoid Cells Exhibit a Dynamic Phenotype in Allergic Airway Inflammation

Group 2 Innate Lymphoid Cells Exhibit a Dynamic Phenotype in Allergic Airway Inflammation

Group 2 innate lymphoid cells (ILC2) are implicated in allergic asthma as an early innate source of the type 2 cytokines IL-5 and IL-13. However, their induction in house dust mite (HDM)-mediated airway inflammation additionally requires T cell activation. It is currently unknown whether phenotypic...

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Bibliographic Details
Main Authors: Bobby W. S. Li, Ralph Stadhouders, Marjolein J. W. de Bruijn, Melanie Lukkes, Dior M. J. M. Beerens, Maarten D. Brem, Alex KleinJan, Ingrid Bergen, Heleen Vroman, Mirjam Kool, Wilfred F. J. van IJcken, Tata Nageswara Rao, Hans Jörg Fehling, Rudi W. Hendriks
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Immunology
Subjects:
allergy
asthma
IL-33
group 2 innate lymphoid cell
house dust mite
mouse model
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01684/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01684/full

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