Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models of Primary and Recurrent Meningioma

Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models of Primary and Recurrent Meningioma

Background. Meningiomas constitute one-third of all primary brain tumors. Although typically benign, about 20% of these tumors recur despite surgery and radiation, and may ultimately prove fatal. There are currently no effective chemotherapies for meningioma. We, therefore, set out to develop patien...

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Bibliographic Details
Main Authors: Huiyuan Zhang, Lin Qi, Yuchen Du, L. Frank Huang, Frank K. Braun, Mari Kogiso, Yanling Zhao, Can Li, Holly Lindsay, Sibo Zhao, Sarah G. Injac, Patricia A. Baxter, Jack M. Su, Clifford Stephan, Charles Keller, Kent A. Heck, Akdes Harmanci, Arif O. Harmanci, Jianhua Yang, Tiemo J. Klisch, Xiao-Nan Li, Akash J. Patel
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cancers
Subjects:
meningioma
xenograft
PDOX
modelling
HDAC inhibitor
Online Access:https://www.mdpi.com/2072-6694/12/6/1478

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https://www.mdpi.com/2072-6694/12/6/1478

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