Versatility of the BID Domain: Conserved Function as Type-IV-Secretion-Signal and Secondarily Evolved Effector Functions Within Bartonella-Infected Host Cells

Versatility of the BID Domain: Conserved Function as Type-IV-Secretion-Signal and Secondarily Evolved Effector Functions Within Bartonella-Infected Host Cells

Bartonella spp. are facultative intracellular pathogens that infect a wide range of mammalian hosts including humans. In order to subvert cellular functions and the innate immune response of their hosts, these pathogens utilize a VirB/VirD4 type-IV-secretion (T4S) system to translocate Bartonella ef...

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Bibliographic Details
Main Authors: Alexander Wagner, Colin Tittes, Christoph Dehio
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Microbiology
Subjects:
Type-IV-secretion
VirB/VirD4
Bartonella
α-proteobacteria
Bartonella effector proteins
relaxases
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00921/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.00921/full

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