BCG-Induced Cross-Protection and Development of Trained Immunity: Implication for Vaccine Design

BCG-Induced Cross-Protection and Development of Trained Immunity: Implication for Vaccine Design

The Bacillus Calmette-Guérin (BCG) is a live attenuated tuberculosis vaccine that has the ability to induce non-specific cross-protection against pathogens that might be unrelated to the target disease. Vaccination with BCG reduces mortality in newborns and induces an improved innate immune response...

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Bibliographic Details
Main Authors: Camila Covián, Ayleen Fernández-Fierro, Angello Retamal-Díaz, Fabián E. Díaz, Abel E. Vasquez, Margarita K. Lay, Claudia A. Riedel, Pablo A. González, Susan M. Bueno, Alexis M. Kalergis
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
BCG
innate immunity
trained immunity
heterologous protection
vaccine
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02806/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02806/full

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