<i>Salvia sclarea</i> L. Essential Oil Extract and Its Antioxidative Phytochemical Sclareol Inhibit Oxytocin-Induced Uterine Hypercontraction Dysmenorrhea Model by Inhibiting the Ca<sup>2+</sup>–MLCK–MLC20 Signaling Cascade: An Ex Vivo and In Vivo Study

<i>Salvia sclarea</i> L. Essential Oil Extract and Its Antioxidative Phytochemical Sclareol Inhibit Oxytocin-Induced Uterine Hypercontraction Dysmenorrhea Model by Inhibiting the Ca<sup>2+</sup>–MLCK–MLC20 Signaling Cascade: An Ex Vivo and In Vivo Study

<i>Salvia sclarea</i> essential oil is used as an aromatic therapy for dysmenorrhea. Sclareol—one of the natural products isolated from <i>S. sclarea</i>—displays anti-inflammatory and antioxidant activities; however, researchers have not yet evaluated the mechanism related t...

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Bibliographic Details
Main Authors: Jennifer Wong, Yi-Fen Chiang, Yin-Hwa Shih, Chun-Hui Chiu, Hsin-Yuan Chen, Tzong-Ming Shieh, Kai-Lee Wang, Tsui-Chin Huang, Yong-Han Hong, Shih-Min Hsia
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Antioxidants
Subjects:
sclareol
<i>Salvia sclarea</i> essential oil
dysmenorrhea
uterine contraction
writhing test
Online Access:https://www.mdpi.com/2076-3921/9/10/991

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https://www.mdpi.com/2076-3921/9/10/991

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