Mitochondrial respiration deficits driven by reactive oxygen species in experimental temporal lobe epilepsy

Metabolic alterations have been implicated in the etiology of temporal lobe epilepsy (TLE), but whether or not they have a functional impact on cellular energy producing pathways (glycolysis and/or oxidative phosphorylation) is unknown. The goal of this study was to determine if alterations in cellu...

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Bibliographic Details
Main Authors: Shane Rowley, Li-Ping Liang, Ruth Fulton, Takahiko Shimizu, Brian Day, Manisha Patel
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114003969