Ocrelizumab: a new milestone in multiple sclerosis therapy

B cells play a central role in the pathogenesis of multiple sclerosis (MS): they are involved in the activation of pro-inflammatory T cells, secretion of pro-inflammatory cytokines and production of autoantibodies directed against myelin. Hence, the use of B cell-depleting monoclonal antibodies as t...

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Bibliographic Details
Main Authors: Patricia Mulero, Luciana Midaglia, Xavier Montalban
Format: Article
Language:English
Published: SAGE Publishing 2018-05-01
Series:Therapeutic Advances in Neurological Disorders
Online Access:https://doi.org/10.1177/1756286418773025