Effect of Donepezil, Tacrine, Galantamine and Rivastigmine on Acetylcholinesterase Inhibition in Dugesia tigrina

Effect of Donepezil, Tacrine, Galantamine and Rivastigmine on Acetylcholinesterase Inhibition in Dugesia tigrina

Dugesia tigrina is a non-parasitic platyhelminth, which has been recently utilized in pharmacological models, regarding the nervous system, as it presents a wide sensitivity to drugs. Our trials aimed to propose a model for an in vivo screening of substances with inhibitory activity of the enzyme ac...

Full description

Bibliographic Details
Main Authors: Cristiane Bezerra da Silva, Arnildo Pott, Selene Elifio-Esposito, Luciane Dalarmi, Kátia Fialho do Nascimento, Ligia Moura Burci, Maislian de Oliveira, Josiane de Fátima Gaspari Dias, Sandra Maria Warumby Zanin, Obdulio Gomes Miguel, Marilis Dallarmi Miguel
Format: Article
Language:English
Published: MDPI AG 2016-01-01
Series:Molecules
Subjects:
Alzheimer’s disease
anticholinesterasic
convulsant activity
spontaneous locomotion
planarian
Online Access:http://www.mdpi.com/1420-3049/21/1/53

Internet

http://www.mdpi.com/1420-3049/21/1/53

Similar Items