Insulin stimulates translocation of human GLUT4 to the membrane in fat bodies of transgenic Drosophila melanogaster.

The fruit fly Drosophila melanogaster is an excellent model system for studies of genes controlling development and disease. However, its applicability to physiological systems is less clear because of metabolic differences between insects and mammals. Insulin signaling has been studied in mammals b...

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Bibliographic Details
Main Authors: Georgeta Crivat, Vladimir A Lizunov, Caroline R Li, Karin G Stenkula, Joshua Zimmerberg, Samuel W Cushman, Leslie Pick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3819322?pdf=render