Development and validation of GLC/MS-procedure of doxylamine quantitative determination

Doxylamine is a hypnotic medicine used for treatment of minor sleep disorders and is a frequent cause of poisoning. Aim. To develop GLC/MS-procedure of doxylamine quantification and carry out step-by-step validation of the developed procedure in the variants of the method of calibration curve, met...

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Bibliographic Details
Main Authors: L. Yu. Klimenko, S. M. Trut, T. A. Kostina, S. M. Poluyan
Format: Article
Language:English
Published: National University of Pharmacy (Kharkiv, Ukraine) 2019-04-01
Series:Журнал органічної та фармацевтичної хімії
Subjects:
Online Access:http://ophcj.nuph.edu.ua/article/view/ophcj.19.974/170522