Combined plasma and tissue genotyping of EGFR T790M benefits NSCLC patients: a real‐world clinical example

Acquired resistance to epidermal growth factor receptor (EGFR)‐tyrosine kinase inhibitors (TKIs) is a prevalent clinical problem in the management of advanced non‐small‐cell lung cancer (NSCLC) with TKI‐sensitizing mutations in the EGFR gene. Third‐generation EGFR‐TKIs have demonstrated potent activ...

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Bibliographic Details
Main Authors: Bing Wei, Chengzhi Zhao, Jun Li, Jiuzhou Zhao, Pengfei Ren, Ke Yang, Chi Yan, Rui Sun, Jie Ma, Yongjun Guo
Format: Article
Language:English
Published: Wiley 2019-05-01
Series:Molecular Oncology
Subjects:
PFS
Online Access:https://doi.org/10.1002/1878-0261.12481