Full regeneration of segmental bone defects using porous titanium implants loaded with BMP-2 containing fibrin gels

Regeneration of load-bearing segmental bone defects is a major challenge in trauma and orthopaedic surgery. The ideal bone graft substitute is a biomaterial that provides immediate mechanical stability, while stimulating bone regeneration to completely bridge defects over a short period. Therefore,...

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Bibliographic Details
Main Authors: J van der Stok, MKE Koolen, MPM de Maat, S Amin Yavari, J Alblas, P Patka, JAN Verhaar, EMM van Lieshout, AA Zadpoor, H Weinans, H Jahr
Format: Article
Language:English
Published: AO Research Institute Davos 2015-03-01
Series:European Cells & Materials
Subjects:
BMP
Online Access:http://www.ecmjournal.org/journal/papers/vol029/pdf/v029a11.pdf