First-in-class positron emission tomography tracer for the glucagon receptor

First-in-class positron emission tomography tracer for the glucagon receptor

Abstract The glucagon receptor (GCGR) is emerging as an important target in anti-diabetic therapy, especially as part of the pharmacology of dual glucagon-like peptide-1/glucagon (GLP-1/GCG) receptor agonists. However, currently, there are no suitable biomarkers that reliably demonstrate GCG recepto...

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Bibliographic Details
Main Authors: Irina Velikyan, Torsten Haack, Martin Bossart, Andreas Evers, Iina Laitinen, Philip Larsen, Oliver Plettenburg, Lars Johansson, Stefan Pierrou, Michael Wagner, Olof Eriksson
Format: Article
Language:English
Published: SpringerOpen 2019-02-01
Series:EJNMMI Research
Subjects:
Glucagon
GCG
GLP-1 receptor
Dual agonist
Type 2 diabetes
Online Access:http://link.springer.com/article/10.1186/s13550-019-0482-0

Internet

http://link.springer.com/article/10.1186/s13550-019-0482-0

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