MURC deficiency in smooth muscle attenuates pulmonary hypertension

MURC deficiency in smooth muscle attenuates pulmonary hypertension

MURC protein regulates the function of caveolae, the small invaginations of the plasma membrane in muscle cells. Here the authors show that by interacting with caveolin proteins, MURC affects RhoA/ROCK signalling and regulates proliferation and migration of pulmonary artery smooth muscle cells, sugg...

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Bibliographic Details
Main Authors: Naohiko Nakanishi, Takehiro Ogata, Daisuke Naito, Kotaro Miyagawa, Takuya Taniguchi, Tetsuro Hamaoka, Naoki Maruyama, Takeru Kasahara, Masahiro Nishi, Satoaki Matoba, Tomomi Ueyama
Format: Article
Language:English
Published: Nature Publishing Group 2016-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12417

Internet

https://doi.org/10.1038/ncomms12417

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