Amyloid β protein impairs motor function via thromboxane A2 in the rat striatum

Amyloid β protein (Aβ) deposits are found in the striatum of patients with Alzheimer disease (AD) showing extrapyramidal motor dysfunction, but neuronal cell loss has not yet been detected. To clarify how Aβ impairs motor function, we analyzed intrastriatally Aβ-injected rats. Unilateral injection o...

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Bibliographic Details
Main Authors:	Tatsurou Yagami, Yukio Takahara, Chiyomi Ishibashi, Gaku Sakaguchi, Naohiro Itoh, Keiichi Ueda, Hitoshi Nakazato, Noboru Okamura, Yoshiharu Hiramatsu, Tsunetoshi Honma, Akinori Arimura, Toshiyuki Sakaeda, Goro Katsuura
Format:	Article
Language:	English
Published:	Elsevier 2004-08-01
Series:	Neurobiology of Disease
Subjects:	Amyloid β protein Thromboxane A2 TXA2 receptor blockers
Online Access:	http://www.sciencedirect.com/science/article/pii/S0969996104000816

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http://www.sciencedirect.com/science/article/pii/S0969996104000816

Amyloid β protein impairs motor function via thromboxane A2 in the rat striatum

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