Bone-seeking nanoplatform co-delivering cisplatin and zoledronate for synergistic therapy of breast cancer bone metastasis and bone resorption

The “vicious cycle” established between tumor growth and osteolysis aggravates the process of breast cancer bone metastasis, leading to life-threatening skeletal-related events that severely reduce survival and quality of life. To effectively interrupt the “vicious cycle”, innovative therapeutic str...

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Bibliographic Details
Main Authors: Yanjuan Huang, Zhanghong Xiao, Zilin Guan, Zishan Zeng, Yifeng Shen, Xiaoyu Xu, Chunshun Zhao
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383520306158