3,5-Diiodothyronine: A Novel Thyroid Hormone Metabolite and Potent Modulator of Energy Metabolism

3,5-Diiodothyronine: A Novel Thyroid Hormone Metabolite and Potent Modulator of Energy Metabolism

Over 30 years of research has demonstrated that 3,5-diiodo-L-thyronine (3,5-T2), an endogenous metabolite of thyroid hormones, exhibits interesting metabolic activities. In rodent models, exogenously administered 3,5-T2 rapidly increases resting metabolic rate and elicits short-term beneficial hypol...

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Bibliographic Details
Main Authors: Rosalba Senese, Pieter de Lange, Giuseppe Petito, Maria Moreno, Fernando Goglia, Antonia Lanni
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Endocrinology
Subjects:
thyroid hormones
energy balance
mitochondria
insulin resistance (IR)
obesity
fatty acids oxidation
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00427/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2018.00427/full

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