Comparative proteomic analysis of Gib2 validating its adaptor function in Cryptococcus neoformans.

Cryptococcus neoformans causes often-fatal fungal meningoencephalitis in immunocompromised individuals. While the exact disease mechanisms remain elusive, signal transduction pathways mediated by key elements such as G-protein α subunit Gpa1, small GTPase Ras1, and atypical Gβ-like/RACK1 protein Gib...

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Bibliographic Details
Main Authors: Gillian O Bruni, Blake Battle, Ben Kelly, Zhengguang Zhang, Ping Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5501510?pdf=render