A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition

<p>Abstract</p> <p>Mechanical hyperalgesia is a clinically-relevant form of pain sensitization that develops through largely unknown mechanisms. TRPA1, a Transient Receptor Potential ion channel, is a sensor of pungent chemicals that may play a role in acute noxious mechanosensatio...

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Bibliographic Details
Main Authors: Huynh Truc, Hwang Sun, Bandell Michael, Peier Andrea M, Petrus Matt, Olney Nicholas, Jegla Tim, Patapoutian Ardem
Format: Article
Language:English
Published: SAGE Publishing 2007-12-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/3/1/40