Effect of oxygen on cardiac differentiation in mouse iPS cells: role of hypoxia inducible factor-1 and Wnt/beta-catenin signaling.

Effect of oxygen on cardiac differentiation in mouse iPS cells: role of hypoxia inducible factor-1 and Wnt/beta-catenin signaling.

<h4>Background</h4>Disturbances in oxygen levels have been found to impair cardiac organogenesis. It is known that stem cells and differentiating cells may respond variably to hypoxic conditions, whereby hypoxia may enhance stem cell pluripotency, while differentiation of multiple cell t...

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Bibliographic Details
Main Authors: Tanya L Medley, Milena Furtado, Nicholas T Lam, Rejhan Idrizi, David Williams, Paul J Verma, Mauro Costa, David M Kaye
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24265804/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24265804/?tool=EBI

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