Equine pituitary pars intermedia dysfunction: a spontaneous model of synucleinopathy

Abstract Equine pituitary pars intermedia dysfunction (PPID) is a common endocrine disease of aged horses that shows a similar pathophysiology as Parkinson’s Disease (PD) with increased levels of α-synuclein (α-syn). While α-syn is thought to play a pathogenic role in horses with PPID, it is unclear...

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Bibliographic Details
Main Authors: Jessica S. Fortin, Ashley A. Hetak, Kelsey E. Duggan, Caroline M. Burglass, Hailey B. Penticoff, Harold C. Schott
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-95396-7