Extracellular Vesicles Derived From Canine Mesenchymal Stromal Cells in Serum Free Culture Medium Have Anti-inflammatory Effect on Microglial Cells

Extracellular Vesicles Derived From Canine Mesenchymal Stromal Cells in Serum Free Culture Medium Have Anti-inflammatory Effect on Microglial Cells

Mesenchymal stem/stromal cells (MSCs) have been used as cell sources for treating dogs with naturally-occurring diseases. Extracellular vesicles (EVs) derived from MSCs are now recognized as pivotal to modulating the immune response and supporting tissue repair. Manufacture of MSC-EVs for clinical a...

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Bibliographic Details
Main Authors: Yukina Kuwahara, Karin Yoshizaki, Hidetaka Nishida, Hiroaki Kamishina, Sadatoshi Maeda, Katsura Takano, Naoki Fujita, Ryohei Nishimura, Jun-ichiro Jo, Yasuhiko Tabata, Hideo Akiyoshi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Veterinary Science
Subjects:
exosome
extracellular vesicles
canine
mesenchymal stromal cells
anti-inflammatory
serum free culture
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2021.633426/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2021.633426/full

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