Nobiletin, a Citrus Flavonoid That Improves Memory Impairment, Rescues Bulbectomy-Induced Cholinergic Neurodegeneration in Mice

Nobiletin, a Citrus Flavonoid That Improves Memory Impairment, Rescues Bulbectomy-Induced Cholinergic Neurodegeneration in Mice

We have recently reported that nobiletin, a citrus flavonoid, improves impaired memory in olfactory-bulbectomized (OBX) mice, which have been widely utilized as a useful paradigm that shares some major clinical features of Alzheimer’s disease. Here, we examined the effects of nobiletin on OBX-induce...

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Bibliographic Details
Main Authors: Akira Nakajima, Tohru Yamakuni, Mitsuya Haraguchi, Naoki Omae, Si-Young Song, Chieko Kato, Osamu Nakagawasai, Takeshi Tadano, Akihito Yokosuka, Yoshihiro Mimaki, Yutaka Sashida, Yasushi Ohizumi
Format: Article
Language:English
Published: Elsevier 2007-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319342240

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http://www.sciencedirect.com/science/article/pii/S1347861319342240

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