The protective effects of the β3 adrenergic receptor agonist BRL37344 against liver steatosis and inflammation in a rat model of high-fat diet-induced nonalcoholic fatty liver disease (NAFLD)

The protective effects of the β3 adrenergic receptor agonist BRL37344 against liver steatosis and inflammation in a rat model of high-fat diet-induced nonalcoholic fatty liver disease (NAFLD)

Abstract Background Our objective was to investigate the efficacy of the beta-3 adrenergic receptor (β3-AR) agonist BRL37344 for the prevention of liver steatosis and inflammation associated with nonalcoholic fatty liver disease (NAFLD). Methods Four groups were established: a control group (given a...

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Bibliographic Details
Main Authors: Ziwen Wang, Shanshan Li, Ruifeng Wang, Liansheng Guo, Dan Xu, Tieyuan Zhang, Yifan Xu, Wenlong Wang, Min Wang, Zhongwei Gan, Xiaobing Wang
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Molecular Medicine
Subjects:
β3-adrenergic receptor
NAFLD
Liver steatosis
Inflammation
Online Access:http://link.springer.com/article/10.1186/s10020-020-00164-4

Internet

http://link.springer.com/article/10.1186/s10020-020-00164-4

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