Oral bioavailability and pharmacokinetics of sildenafil citrate dry foam tablets in rats

Sildenafil has low water solubility and oral bioavailability. Dry foam formulations of solid dosage forms of poorly water-soluble drugs may exhibit improved dissolution and bioavailability. We previously developed a sildenafil citrate dry foam tablet formulation and found that it had an improved dis...

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Bibliographic Details
Main Authors: Somchai Sawatdee, Apichart Atipairin, Attawadee Sae Yoon, Teerapol Srichana, Narumon Changsan, Tan Suwandecha, Wirot Chanthorn, Atchara Phoem
Format: Article
Published: Taylor & Francis Group 2018-01-01
Series:Cogent Medicine
Online Access:http://dx.doi.org/10.1080/2331205X.2018.1510821