Oral bioavailability and pharmacokinetics of sildenafil citrate dry foam tablets in rats

Oral bioavailability and pharmacokinetics of sildenafil citrate dry foam tablets in rats

Sildenafil has low water solubility and oral bioavailability. Dry foam formulations of solid dosage forms of poorly water-soluble drugs may exhibit improved dissolution and bioavailability. We previously developed a sildenafil citrate dry foam tablet formulation and found that it had an improved dis...

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Bibliographic Details
Main Authors: Somchai Sawatdee, Apichart Atipairin, Attawadee Sae Yoon, Teerapol Srichana, Narumon Changsan, Tan Suwandecha, Wirot Chanthorn, Atchara Phoem
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Cogent Medicine
Subjects:
sildenafil citrate
pharmacokinetics
bioavailability
dry foam tablet
Online Access:http://dx.doi.org/10.1080/2331205X.2018.1510821

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