Endothelial Calcineurin Signaling Restrains Metastatic Outgrowth by Regulating Bmp2

Endothelial Calcineurin Signaling Restrains Metastatic Outgrowth by Regulating Bmp2

Summary: Calcineurin/NFAT signaling is active in endothelial cells and is proposed to be an essential component of the tumor angiogenic response. Here, we investigated the role of endothelial calcineurin signaling in vivo in physiological and pathological angiogenesis and tumor metastasis. We show t...

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Bibliographic Details
Main Authors: Stefanie Hendrikx, Sanja Coso, Borja Prat-Luri, Laureline Wetterwald, Amélie Sabine, Claudio A. Franco, Sina Nassiri, Nadine Zangger, Holger Gerhardt, Mauro Delorenzi, Tatiana V. Petrova
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719300257

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http://www.sciencedirect.com/science/article/pii/S2211124719300257

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