Huntington’s disease modeling on HEK293 cell line
Huntington’s disease is a hereditary neurodegenerative disorder caused by CAG trinucleotide repeat expansion in the first exon of HTT gene. The mutant HTT protein has an elongated polyglutamine tract and forms aggregates in the nuclei and cytoplasm of the striatal neurons. The pathological processes...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences
2017-12-01
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| Series: | Vavilovskij Žurnal Genetiki i Selekcii |
| Subjects: | |
| Online Access: | https://vavilov.elpub.ru/jour/article/view/1236 |