An N-Terminal Fragment of Yeast Ribosomal Protein L3 Inhibits the Cytotoxicity of Pokeweed Antiviral Protein in Saccharomyces cerevisiae

We have previously shown that ribosomal protein L3 is required for pokeweed antiviral protein (PAP), a type I ribosome inactivating protein, to bind to ribosomes and depurinate the α-sarcin/ricin loop (SRL) in yeast. Co-expression of the N-terminal 99 amino acids of yeast L3 (L3Δ99) with PAP in tran...

Full description

Bibliographic Details
Main Authors: Rong Di, Nilgun E. Tumer
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/6/4/1349