Enhanced therapeutic effects of MSC-derived extracellular vesicles with an injectable collagen matrix for experimental acute kidney injury treatment

Enhanced therapeutic effects of MSC-derived extracellular vesicles with an injectable collagen matrix for experimental acute kidney injury treatment

Abstract Background Mesenchymal stem cell (MSC)-derived extracellular vesicles (EVs) have been shown to have therapeutic potential for ischemic diseases and are considered an alternative to cell therapy. However, the low retention and poor stability of EVs post-transplantation in vivo remain obstacl...

Full description

Bibliographic Details
Main Authors: Yue Liu, Jian Cui, Hongfen Wang, Kamal Hezam, Xiaotong Zhao, Haoyan Huang, Shang Chen, Zhibo Han, Zhong-Chao Han, Zhikun Guo, Zongjin Li
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cell (MSC)
Extracellular vehicles (EVs)
Collagen matrix
Molecular imaging
Acute kidney injury (AKI)
Online Access:http://link.springer.com/article/10.1186/s13287-020-01668-w

Internet

http://link.springer.com/article/10.1186/s13287-020-01668-w

Similar Items