Pep2Path: automated mass spectrometry-guided genome mining of peptidic natural products.

Nonribosomally and ribosomally synthesized bioactive peptides constitute a source of molecules of great biomedical importance, including antibiotics such as penicillin, immunosuppressants such as cyclosporine, and cytostatics such as bleomycin. Recently, an innovative mass-spectrometry-based strateg...

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Bibliographic Details
Main Authors: Marnix H Medema, Yared Paalvast, Don D Nguyen, Alexey Melnik, Pieter C Dorrestein, Eriko Takano, Rainer Breitling
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-09-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4154637?pdf=render