ERK/Nrf2 pathway activation by caffeic acid in HepG2 cells alleviates its hepatocellular damage caused by t-butylhydroperoxide-induced oxidative stress

Abstract Background Several studies have found that caffeic acid (CA), a well-known phytochemical, displays important antioxidant and anti-cancer activities. However, no evidence exists on the protective effect and its mechanisms that CA treatment alone has against oxidative stress induced by tert-b...

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Bibliographic Details
Main Authors: Sung-Yong Yang, Min Cheol Pyo, Mi-Hyun Nam, Kwang-Won Lee
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12906-019-2551-3