Fluorescence-Based Ratiometric Analysis of Sperm Centrioles (FRAC) Finds Patient Age and Sperm Morphology Are Associated With Centriole Quality

Fluorescence-Based Ratiometric Analysis of Sperm Centrioles (FRAC) Finds Patient Age and Sperm Morphology Are Associated With Centriole Quality

A large proportion of infertility and miscarriage causes are unknown. One potential cause is a defective sperm centriole, a subcellular structure essential for sperm motility and embryonic development. Yet, the extent to which centriolar maladies contribute to male infertility is unknown due to the...

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Bibliographic Details
Main Authors: Katerina A. Turner, Emily L. Fishman, Mariam Asadullah, Brooke Ott, Patrick Dusza, Tariq A. Shah, Puneet Sindhwani, Nagalakshmi Nadiminty, Emanuela Molinari, Pasquale Patrizio, Barbara S. Saltzman, Tomer Avidor-Reiss
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
centriole
infertility
sperm
fluorescence
method
age
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.658891/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.658891/full

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