Signal Transduction Profiling of Angiotensin II Type 1 Receptor With Mutations Associated to Atrial Fibrillation in Humans

Signal Transduction Profiling of Angiotensin II Type 1 Receptor With Mutations Associated to Atrial Fibrillation in Humans

The AT1 receptor (AT1R) has a major role in the Renin-Angiotensin System, being involved in several physiological events including blood pressure control and electrolyte balance. The AT1R is a member of the G protein coupled receptors (GPCR) family, classically known to couple Gαq and engage β-arres...

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Bibliographic Details
Main Authors: Sarah C. Simões, André L. Balico-Silva, Lucas T. Parreiras-e-Silva, André L. B. Bitencourt, Michel Bouvier, Claudio M. Costa-Neto
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Pharmacology
Subjects:
Angiotensin II receptor
AngII
AT1 receptor
signalling
cardiovascular diseases
mutations
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.600132/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.600132/full

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