Population pharmacokinetics of artesunate and dihydroartemisinin in pregnant and non-pregnant women with uncomplicated Plasmodium falciparum malaria in Burkina Faso: an open label trial [version 2; peer review: 2 approved]

Background: Malaria during pregnancy is a major health risk for both the mother and the foetus. Pregnancy has been shown to influence the pharmacokinetics of a number of different antimalarial drugs. This might lead to an under-exposure in these patients which could increase the risk of treatment fa...

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Main Authors: Sofia Birgersson, Innocent Valea, Halidou Tinto, Maminata Traore-Coulibaly, Laeticia C. Toe, Richard M. Hoglund, Jean-Pierre Van Geertruyden, Stephen A. Ward, Umberto D’Alessandro, Angela Abelö, Joel Tarning
Format: Article
Language:English
Published: Wellcome 2020-01-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/4-45/v2