Post-Transplant Cyclophosphamide and Tacrolimus—Mycophenolate Mofetil Combination Governs GVHD and Immunosuppression Need, Reducing Late Toxicities in Allogeneic Peripheral Blood Hematopoietic Cell Transplantation from HLA-Matched Donors

Post-Transplant Cyclophosphamide and Tacrolimus—Mycophenolate Mofetil Combination Governs GVHD and Immunosuppression Need, Reducing Late Toxicities in Allogeneic Peripheral Blood Hematopoietic Cell Transplantation from HLA-Matched Donors

Combined direct antineoplastic activity and the long-lasting immunological effects of allogeneic hematopoietic cell transplant (HCT) can cure many hematological malignancies, but broad adoption requires non-relapse mortality (NRM) rates and graft-versus-host disease (GVHD) control. Recently, posttra...

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Bibliographic Details
Main Authors: Fabrizio Carnevale-Schianca, Daniela Caravelli, Susanna Gallo, Paolo Becco, Luca Paruzzo, Stefano Poletto, Alessandra Polo, Monica Mangioni, Milena Salierno, Massimo Berger, Rosanna Pessolano, Francesco Saglio, Daniela Gottardi, Delia Rota-Scalabrini, Giovanni Grignani, Marco Fizzotti, Ivana Ferrero, Pio Manlio Mirko Frascione, Lorenzo D’Ambrosio, Valentina Gaidano, Loretta Gammaitoni, Dario Sangiolo, Andrea Saglietto, Elena Vassallo, Alessandro Cignetti, Massimo Aglietta, Franca Fagioli
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Journal of Clinical Medicine
Subjects:
allogeneic hematopoietic cell transplantation
graft-versus-host disease
post-transplant cyclophosphamide
immunosuppression modulation
long term outcomes
Online Access:https://www.mdpi.com/2077-0383/10/6/1173

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https://www.mdpi.com/2077-0383/10/6/1173

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