Steroid hormone receptors and prostate cancer: role of structural dynamics in therapeutic targeting

Steroid hormone receptors and prostate cancer: role of structural dynamics in therapeutic targeting

Steroid hormone receptors (SHRs) act in cell type- and gene-specific manner through interactions with coregulatory proteins to regulate numerous physiological and pathological processes at the level of gene regulation. Binding of steroid receptor modulator (SRM) ligand leads to allosteric changes in...

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Bibliographic Details
Main Author: Raj Kumar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Asian Journal of Andrology
Subjects:
allosteric regulation; coregulatory proteins; endocrine cancers; intrinsically disordered proteins; steroid hormone receptors; structural dynamics; transactivation activity
Online Access:http://www.ajandrology.com/article.asp?issn=1008-682X;year=2016;volume=18;issue=5;spage=682;epage=686;aulast=Kumar

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http://www.ajandrology.com/article.asp?issn=1008-682X;year=2016;volume=18;issue=5;spage=682;epage=686;aulast=Kumar

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