Exploring the In Vivo Anti-Inflammatory Actions of Simvastatin-Loaded Porous Microspheres on Inflamed Tenocytes in a Collagenase-Induced Animal Model of Achilles Tendinitis

Exploring the In Vivo Anti-Inflammatory Actions of Simvastatin-Loaded Porous Microspheres on Inflamed Tenocytes in a Collagenase-Induced Animal Model of Achilles Tendinitis

Tendon rupture induces an inflammatory response characterized by release of pro-inflammatory cytokines and impaired tendon performance. This study sought to investigate the therapeutic effects of simvastatin-loaded porous microspheres (SIM/PMSs) on inflamed tenocytes in vitro and collagenase-induced...

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Bibliographic Details
Main Authors: Chandong Jeong, Sung Eun Kim, Kyu-Sik Shim, Hak-Jun Kim, Mi Hyun Song, Kyeongsoon Park, Hae-Ryong Song
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:International Journal of Molecular Sciences
Subjects:
Achilles tendinitis
simvastatin
porous microspheres
anti-inflammation
tendon healing
Online Access:http://www.mdpi.com/1422-0067/19/3/820

Internet

http://www.mdpi.com/1422-0067/19/3/820

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