PolyI:C Upregulated CCR5 and Promoted THP-1-Derived Macrophage Chemotaxis via TLR3/JMJD1A Signalling

Objective: This study aimed to evaluate the specific roles of polyinosinic:polycytidylic acid (polyI:C) in macrophage chemotaxis and reveal the potential regulatory mechanisms related to chemokine receptor 5 (CCR5). Materials and Methods: In this experimental study, THP-1-derived macrophages (THP1...

Full description

Bibliographic Details
Main Authors: Xiaoxiao Yu, Huayang Wang, Hongjia Shao, Cuijuan Zhang, Xiuli Ju, Jie Yang
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2020-10-01
Series:Cell Journal
Subjects:
Online Access:https://celljournal.org/journal/article/abstract/6713