Altered cross-bridge properties in skeletal muscle dystrophies

Force and motion generated by skeletal muscle ultimately depends on the cyclical interaction of actin with myosin. This mechanical process is regulated by intracellular Ca2+ through the thin filament-associated regulatory proteins i.e.; troponins and tropomyosin. Muscular dystrophies are a group of...

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Bibliographic Details
Main Authors: Aziz eGuellich, Elisa eNegroni, Valérie eDecostre, Alexandre eDemoule, Catherine eCoirault
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00393/full