Vps3 and Vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions

Vps3 and Vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions

The CORVET complex is a multi-subunit complex that regulates fusion between early endosomes. Here the authors show that the CORVET subunits Vps3 and Vps8 also regulate vesicular transport from early to recycling endosomes and are required for recycling integrins to the plasma membrane.

Bibliographic Details
Main Authors: C. T. H. Jonker, R. Galmes, T. Veenendaal, C. ten Brink, R. E. N. van der Welle, N. Liv, J. de Rooij, A. A. Peden, P. van der Sluijs, C. Margadant, J. Klumperman
Format: Article
Language:English
Published: Nature Publishing Group 2018-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-03226-8

Internet

https://doi.org/10.1038/s41467-018-03226-8

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