Vps3 and Vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions
The CORVET complex is a multi-subunit complex that regulates fusion between early endosomes. Here the authors show that the CORVET subunits Vps3 and Vps8 also regulate vesicular transport from early to recycling endosomes and are required for recycling integrins to the plasma membrane.
Bibliographic Details
| Main Authors: |
C. T. H. Jonker,
R. Galmes,
T. Veenendaal,
C. ten Brink,
R. E. N. van der Welle,
N. Liv,
J. de Rooij,
A. A. Peden,
P. van der Sluijs,
C. Margadant,
J. Klumperman |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2018-02-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-018-03226-8
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