Unwanted Hormonal and Metabolic Effects of Postoperative Adjuvant Mitotane Treatment for Adrenocortical Cancer

Unwanted Hormonal and Metabolic Effects of Postoperative Adjuvant Mitotane Treatment for Adrenocortical Cancer

Mitotane is widely used for the treatment of adrenocortical cancer (ACC), although the drug-related toxicity complicates its use. The aim of this study is to assess comprehensively the different endocrine and metabolic unwanted effects of the drug, and to provide data on the supportive therapies. We...

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Bibliographic Details
Main Authors: Vittoria Basile, Soraya Puglisi, Anna Calabrese, Anna Pia, Paola Perotti, Alfredo Berruti, Giuseppe Reimondo, Massimo Terzolo
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
adrenocortical carcinoma
adrenal insufficiency
endocrine effects
hypercholesterolemia
hypogonadism
hypothyroidism
Online Access:https://www.mdpi.com/2072-6694/12/9/2615

Internet

https://www.mdpi.com/2072-6694/12/9/2615

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