The use of human induced pluripotent stem cells to screen for developmental toxicity potential indicates reduced potential for non-combusted products, when compared to cigarettes

The use of human induced pluripotent stem cells to screen for developmental toxicity potential indicates reduced potential for non-combusted products, when compared to cigarettes

devTOX quickPredict (devTOXqP) is a metabolomics biomarker-based assay that utilises human induced pluripotent stem (iPS) cells to screen for potential early stage embryonic developmental toxicity in vitro. Developmental toxicity potential is assessed based on the assay endpoint of the alteration in...

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Bibliographic Details
Main Authors: Liam Simms, Kathryn Rudd, Jessica Palmer, Lukasz Czekala, Fan Yu, Fiona Chapman, Edgar Trelles Sticken, Roman Wieczorek, Lisa Maria Bode, Matthew Stevenson, Tanvir Walele
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Current Research in Toxicology
Subjects:
E-cigarettes
Developmental toxicity
Cigarettes
Nicotine
Human induced pluripotent stem cells
In vitro reproduction assay
Online Access:http://www.sciencedirect.com/science/article/pii/S2666027X20300189

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http://www.sciencedirect.com/science/article/pii/S2666027X20300189

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