Consequences of a human TRPA1 genetic variant on the perception of nociceptive and olfactory stimuli.

BACKGROUND: TRPA1 ion channels are involved in nociception and are also excited by pungent odorous substances. Based on reported associations of TRPA1 genetics with increased sensitivity to thermal pain stimuli, we therefore hypothesized that this association also exists for increased olfactory sens...

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Bibliographic Details
Main Authors: Michael Schütz, Bruno G Oertel, Dirk Heimann, Alexandra Doehring, Carmen Walter, Violeta Dimova, Gerd Geisslinger, Jörn Lötsch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4005389?pdf=render