Direct Visualization of Amlodipine Intervention into Living Cells by Means of Fluorescence Microscopy

Direct Visualization of Amlodipine Intervention into Living Cells by Means of Fluorescence Microscopy

Amlodipine, a unique long-lasting calcium channel antagonist and antihypertensive drug, has weak fluorescence in aqueous solutions. In the current paper, we show that direct visualization of amlodipine in live cells is possible due to the enhanced emission in cellular environment. We examined the im...

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Bibliographic Details
Main Authors: Christine Quentin, Rūta Gerasimaitė, Alexandra Freidzon, Levon S. Atabekyan, Gražvydas Lukinavičius, Vladimir N. Belov, Gyuzel Y. Mitronova
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Molecules
Subjects:
amlodipine
fluorescence
live cell imaging
microscopy
lysosomes
Online Access:https://www.mdpi.com/1420-3049/26/10/2997

Internet

https://www.mdpi.com/1420-3049/26/10/2997

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